Medical Devices
New exercise guidelines are being developed that will give cancer survivors a comprehensive plan on how to safely start or maintain a physical activity program - and, in turn, enjoy a higher quality of life after battling the disease.
"In a new report released yesterday, the government watchdog group Common Cause found that major health care interests have spent upwards of $1.4 million a day to lobby Capitol Hill so far this year," the National Journal reports. This political spending amount represents a 73 percent increase since 2000. In addition, the report finds that campaign contributions to members of Congress jumped $40 million since 2000, to $94 million in the 2008 election cycle (Krigman, 6/24).
Polk County, Fla., health officials have made educating the black community a top priority in addressing HIV/AIDS in the state, where blacks are disproportionately affected by the virus, the Lakeland Ledger reports. The Polk County Health Department has expanded its community outreach and testing efforts to different types of settings such as beauty salons, community centers and churches. County outreach workers hope that offering education and screening in such settings will encourage residents to get informed and tested for HIV (Williams Adams [1], Lakeland Ledger, 6/24). In addition, the Ledger examined the complex issues the black community faces with regard to HIV/AIDS and the barriers that need be addressed to reduce the impact of HIV/AIDS on minorities (Williams Adams, Lakeland Ledger, 6/25). The Ledger also profiled Bonnie Munson, a local resident who performs volunteer outreach efforts in her community, including distributing condoms and informational material to other residents (Williams Adams [2], Lakeland Ledger, 6/24).
The H1N1 (swine flu) virus has reached the sub-Saharan African countries of Cape Verde, Ethiopia and Ivory Coast, according to the WHO, the AP/Boston Herald reports. Last week, South Africa became the first country in the region to confirm a 12-year-old, who had returned from the U.S., tested positive for the H1N1 virus.
FDA on Wednesday approved Watson Pharmaceuticals" generic version of the emergency contraceptive Plan B, the Wall Street Journal reports. The generic drug will be available without a prescription to women ages 18 and older on Aug. 24, when Duramed Pharmaceuticals" market exclusivity for Plan B expires (Kalish, Wall Street Journal, 6/25). The generic version will be available to women ages 17 and younger with a prescription, according to an FDA press release (FDA Web site, 6/24). Watson will market the generic version under the name Next Choice (AP/Washington Post, 6/24).A one-time use pack of the brand-name product, Plan B, currently costs $49.99 through the online retailer DrugStore.com. According to Bloomberg, generic drugs usually cost 30% to 80% less than brand-name versions (Larkin, Bloomberg, 6/24).
Reviewing the records of 577 breast cancer patients, Fox Chase Cancer Center researchers found that women with newly diagnosed breast cancer who receive a breast MRI are more likely to receive a mastectomy after their diagnosis and may face delays in starting treatment. The study demonstrates that, despite the lack of evidence of their benefit, routine use of MRI scans in women newly diagnosed with breast cancer increased significantly between 2004 and 2005, and again in 2006.
President Barack Obama"s signature on a bill this week to grant the Food and Drug Administration (FDA) regulatory authority over tobacco was historic, and represents a step in the march to eliminate tobacco use in this country by 2047, two national tobacco experts said recently (June 25).
For years, proponents have touted the benefits of embryonic stem cell research, but the potential therapies still face hurdles. Side effects such as tumor development, a lack of an effective and long-term animal model to test new therapies, and genetic incompatibility between the host and donor cells are some of the problems faced by researchers. Now, scientists at the University of Missouri have developed the ability to take regular cells from a pig"s connective tissues, known as fibroblasts, and transform them into stem cells, eliminating several of these hurdles. The new study appeared in a recent issue of the Proceedings of the National Academy of Sciences (PNAS).
UCB announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA) has issued a positive opinion recommending that the European Commission grants a marketing authorisation for Cimzia® (certolizumab pegol), in combination with methotrexate (MTX), for the treatment of moderate to severe active rheumatoid arthritis in adult patients when the response to disease-modifying anti-rheumatic drugs (DMARDs) including MTX, has been inadequate. In these patients, Cimzia® can be given as monotherapy in case of intolerance to MTX or when continued treatment with MTX is inappropriate. Cimzia® has been shown to reduce the rate of progression of joint damage as measured by X-ray and to improve physical function, when given in combination with MTX.
A test commonly used to help identify women with diabetes during pregnancy may be an accurate, convenient and inexpensive way to screen the general population for unrecognized diabetes and prediabetes, according to Emory University researchers.
In a landmark technical achievement, investigators in the Vanderbilt Center for Structural Biology have used nuclear magnetic resonance (NMR) methods to determine the structure of the largest membrane-spanning protein to date.
Childhood physical abuse is associated with elevated rates of cancer in adulthood, according to a new study by University of Toronto researchers.
Veritide Ltd., a developer of innovative biological identification and detection solutions, today reported that new independent data to be presented at the Biodetection Technologies 2009 conference confirm the exceptional accuracy of its Ceeker™ (pronounced "seeker") portable bacterial detection device in discriminating between anthrax spores and similar-looking hoax substances. The data show that in over two weeks of testing at the Midwest Research Institute in Florida, the company"s Ceeker scanner accurately identified 100% of the anthrax samples used and was correct in 95% of tests involving hoax substances. These test results are consistent with similar results produced last year by a New Zealand forensic testing agency, Environmental Science and Research (ESR).
People who eat lots of soy products have better lung function and are less likely to develop the smoking-associated lung disease COPD (Chronic Obstructive Pulmonary Disease). A study published in BioMed Central"s open access journal Respiratory Research has shown that consumption of a wide variety of soy products can be associated with a reduction in the risk of COPD and other respiratory symptoms.
The NMC announced the appointment of Roger Thompson as its new Director of Standards and Registration.
An enzyme that naturally occurs in the brain helps destroy the mutated protein that is the most common cause of inherited Parkinson"s disease, researchers at UT Southwestern Medical Center have found.
Combating high blood pressure is a global challenge. But while developed countries have enjoyed reductions in cardiovascular disease over recent decades, Latin America has been less fortunate. In fact new research published in the journal Therapeutic Advances in Cardiovascular Disease shows that high blood pressure is on the increase in many Latin American countries, a situation set to worsen unless immediate action is taken.
New York"s Empire State Stem Cell Board earlier this month decided to allow embryonic stem cell researchers who receive state funding to compensate women for donating their eggs for use in research, making New York the first state to enact such a policy, the Washington Post reports (Stein, Washington Post, 6/26). According to the New York Times, the New York state Legislature in 2007 allotted $600 million for an 11-year stem cell research plan (Nelson, New York Times, 6/26). Under the board"s decisions, researchers receiving the state funding may pay women up to $10,000 to compensate them for the time, discomfort and expenses associated with egg donation. David Hohn, vice chair of the board"s two committees that endorsed the decision, said that the board "could not distinguish ethically between the payment for in vitro fertilization, which is very well precedented, and the compensation for donation for research." The board said researchers should follow the same guidelines as infertility clinics that receive donated eggs for infertile couples. Under those guidelines, payments exceeding $5,000 must be justified, and those exceeding $10,000 are considered excessive (Washington Post, 6/26). Robert Klitzman, director of the master"s degree program in bioethics at Columbia University and a member of the stem cell board"s ethics committee, said the payments will be carefully evaluated by an institutional review board (New York Times, 6/26).The Post reports that the decision goes against policies in other states that offer funding for embryonic stem cell research, as well as against current guidelines from scientific organizations like the National Academy of Sciences (Washington Post, 6/26). NAS guidelines, for example, prohibit paying women for eggs used in stem cell research. Similarly, the internal guidelines for New York-based groups like Rockefeller University, Cornell University and the Sloan-Kettering Institute prohibit financial compensation for donated eggs. However, researchers say that efforts to recruit unpaid donors have been unsuccessful and that the board"s decision will give New York an advantage in stem cell research (New York Times, 6/26). The decision was welcomed by scientists and other proponents of stem cell research, who said it will allow them to further research in areas like therapeutic cloning. The process, also known as somatic cell nuclear transfer, involves replacing the genetic material in a human egg with genes from the nucleus of a patient"s cell. The egg is then developed into an early embryo, which, in theory, could be used to produce stem cells that the patient"s immune system would not reject. Although the procedure has been unsuccessful so far, researchers say the board"s decision will help attract more donors, which will allow for more experiments. Egg donation involves weeks of hormone injections to stimulate the ovaries and a painful egg extraction procedure, which carries rare but serious risks. Other attempts at soliciting women to donate eggs for stem cell research have been unsuccessful, according to the Post.Some critics of the board"s decision said that paying women for eggs could lead to exploitation, especially for low-income women. Thomas Berg -- a Roman Catholic priest who is director of the Westchester Institute for Ethics and the Human Person and a member of the Empire State Stem Cell Board"s ethics committee -- said that in the current economic recession, paying a woman $10,000 to participate in a research project is an "undue inducement." He added that he thinks it "manipulates women" and "creates a trafficking in human body parts." Other opponents of the decision questioned if compensating women who donate eggs for research is indeed equivalent to the process for infertility treatments. Jonathan Moreno, a professor of bioethics at the University of Pennsylvania, said that donors recognize that egg donation for infertility treatments is a "very concrete good for society" but that "you can"t be sure any biological material you collect for research wi
"A federal judge on Thursday blocked a $2 hourly wage cut for California in-home care workers that was slated to begin July 1, potentially increasing California"s budget deficit by another $98 million," The Sacramento Bee reports. In an oral injunction, the judge ordered the state "to continue paying up to $12.10 in wages and benefits to In-Home Supportive Services workers, according to parties on both sides of the suit. As part of the February budget deal, Gov. Arnold Schwarzenegger and the Legislature approved a cut to $10.10 per hour - $9.50 in wages and 60 cents in benefits." The lawsuit was filed by The Service Employees International Union, which represents IHSS workers. "IHSS advocates say the system saves the state money because recipients would otherwise use more costly care provided by nursing facilities. But the Senate Office of Oversight and Outcomes this year also found that the IHSS program lacks sufficient oversight and suffers from fraud and abuse" (Yamamura, 6/26).
In Ohio, a nursing home coalition warns of "life-threatening health risks" if Medicaid reimbursements are cut under Gov. Ted Strickland"s proposed budget plan while diabetes patients in the state are threatened by a lack of coverage.
Mexican President Felipe Calderon and Chilean President Michelle Bachelet on Thursday emphasized the importance of developing countries having access to a vaccine that offers protection against the H1N1 (swine flu), "that has killed over 200 people and infected tens of thousands worldwide," AFP/MSN Philippine News reports.
Kenya"s Medical Services Permanent Secretary James Ole Kiyiapi announced Thursday that the government is in negotiations with PEPFAR for support in building additional blood transfusion centers in the country, Capital News reports. In an opening address at the 5th International Africa Society for Blood Transfusion, Ole Kiyiapi said the government estimates it will cost about Sh230 million ($2.99 million) to build the new centers and train appropriate staff.
In malaria-endemic areas, vitamin A supplements - which cost about 2 U.S. cents each - can help reduce infections in children by one-third, according to a study published in the Malaria Journal, IRIN reports. The study analyzed results from previous studies conducted in Burkina Faso, Ghana and Papua New Guinea since 1995. It found that vitamin A supplements decreased malaria cases by one-third in Papua New Guinea and Burkina Faso.
The Kaiser Family Foundation, ahead of National HIV Testing Day on Saturday, has released new and updated informational res on HIV testing in the U.S., including a fact sheet that provides HIV testing statistics, policies and CDC recommendations. In addition, the Foundation released two survey briefs, which examine the public"s attitudes, experiences and knowledge related to HIV testing, one of which focuses on black residents. The briefs are based on the 2009 Survey of Americans on HIV/AIDS released this spring. Information regarding HIV testing by state also is available through statehealthfacts.org (Kaiser Family Foundation release, 6/24).
The AMA has written to Federal MPs and Senators urging them to support a number of key policy measures to reduce preventable health problems linked to excessive alcohol use, obesity and smoking.
When a patient is diagnosed with metastatic disease the primary site of the cancer is usually, but not always, evident. When the origin of the cancer is not identified it is described as a Cancer of Unknown Primary site, or CUP.
This Friday 26 June, Alzheimer"s Society representatives and sports personality Micky Quinn will join Richard Dunwoody, in his quest to walk 1,000 miles in 1,000 hours.
Eighty percent of Canadians believe Canada"s airlines should offer some pet-free flights to protect the health and safety of passengers and crew members, according to a new survey released today by The Canadian Lung Association. The findings come as Air Canada prepares to join WestJet in allowing pets to travel in the passenger cabin of airplanes - pet allergens can trigger serious or even life-threatening reactions in people with lung diseases like asthma and COPD.
IDF, WHF and UICC join forces
The two leading bodies representing GPs in the UK have backed a call by the Wellcome Trust for clearer guidance for GPs to ensure medical records can be safely used in research.
A research article published in the World Journal of Gastroenterology addresses this question. This is believed to be the first study to investigate the effect of PBD in ampullary cancer. A team of gastroenterologists led by Dr Steven Joseph Mesenas and hepatobiliary surgeons at Singapore General Hospital divided 82 patients with ampullary cancer planned for surgical resection into those with PBD (n = 35) and those without (n = 47). The authors looked into various outcomes after surgery, such as pancreatic leakage, wound infection, bile leakage, infectious morbidity, intra-abdominal or gastrointestinal bleeding, intra-abdominal abscess, delayed gastric emptying and mortality. They found that the PBD group had a significantly reduced wound infection rate compared to the non-PBD group. More studies should be conducted to assess this benefit, especially in ampullary cancer patients.
Perhaps the only thing harder than sticking to a weight loss plan is starting a new one after yet another failed diet attempt. Physicians Sharon Herring and Stephanie Ward recognize such "diet fatigue" in their patients and their own families. Now, they"re offering a "fresh start" to the diet-weary.
In a leading medical journal this week US researchers describe the 90-year history of swine flu and warn about working with "freezer" viruses,
-- 17 confirmed cases in Wales, with 0 new cases.
Sixty-two percent of U.S. residents want Supreme Court nominee Sonia Sotomayor to be confirmed, and 55% say she is "about right" on a liberal-to-conservative scale, according to a recent Washington Post/ABC News poll, the Post reports. For the survey, pollsters randomly surveyed a national sample of 1,001 adults by telephone between June 18 and June 21. The poll has a margin of sampling error of plus or minus three percentage points.The poll found that about three-fourths of abortion-rights supporters want Sotomayor to be confirmed, compared with less than half of abortion-rights opponents. According to the poll, six in 10 U.S. residents would want the new Supreme Court justice to vote to uphold Roe v. Wade. Most Republican men would want the next Supreme Court justice to vote to overturn Roe, while Republican women were split about evenly on the issue, the poll found. The poll also found that support for Sotomayor"s confirmation was equal between men and women. In addition, nearly eight in 10 Democrats and about two-thirds of independents said they supported Sotomayor"s confirmation, compared with 36% of Republicans. The poll found that most Republicans deemed Sotomayor a "more liberal" nominee than they would prefer. Among Republicans, those self-identifying as conservative Republicans were largely opposed to Sotomayor"s confirmation, with more than seven in 10 conservative Republicans saying she is too liberal. Sotomayor received support from Republicans self-identifying as moderate or liberal, with fewer than four in 10 saying she is too liberal. However, about one in five who opposed Sotomayor"s confirmation said that she is not liberal enough. The poll also found that among the 33% of U.S. residents who said that Sotomayor"s gender plays a role, more than twice as many said that is a positive attribute as opposed to a negative attribute (Cohen/Barnes, Washington Post, 6/28).Sessions Requests More InformationSenate Judiciary Committee ranking Republican Jeff Sessions (Ala.) on Friday sent a letter to the White House requesting additional information on Sotomayor, the New York Times" "The Caucus" reports. According to Sessions, the Obama administration has yet to provide members of the committee with information about a number of cases that Sotomayor brought to trial while working as a district attorney in New York. In addition, Sessions requested information regarding a case that Sotomayor argued on appeal. He also requested information about her work with Latino Justice PRLDEF, formerly known as the Puerto Rican Legal Defense and Education Fund. Sotomayor"s confirmation hearing is scheduled to begin July 13. Republicans have criticized the schedule, saying it gives them insufficient time to review Sotomayor"s record. Democrats have said that Republicans are seeking to create unnecessary delays and noted that the timeline is similar to that of past nominees (Herszenhorn, "The Caucus," New York Times, 6/26).
A federal judge will hear oral arguments on July 17 regarding a lawsuit challenging a South Dakota law that requires doctors to tell women seeking abortions that the procedure will end a human life, the AP/Sioux City Journal reports. Planned Parenthood, which operates the state"s only abortion clinic, appealed the law after it was passed in 2005. U.S. District Judge Karen Schreier temporarily prevented the law from going into effect, but the 8th U.S. Circuit Court of Appeals in July 2008 overruled that order, and the state began enforcing the law. According to the AP/Journal, Schreier will decide during the hearing whether to grant motions for summary judgment and will consider Planned Parenthood"s request to stop the state from imposing sanctions over the law"s requirements (AP/Sioux City Journal, 6/26).
Reuters reports that "President Barack Obama"s drive to overhaul the U.S. healthcare system may be back on track thanks to Senate efforts to cut the price tag to $1 trillion, but a bipartisan deal on the sweeping proposal still is far from certain ... Senate Finance Committee Chairman Max Baucus was upbeat last week after announcing that panel members had found ways to bring the price tag to about $1 trillion over 10 years, down from an earlier estimate of a staggering $1.6 trillion ... Instead, the core group of negotiators -- three Democrats and four Republicans -- issued a tepid statement on Thursday merely affirming their commitment to continue negotiations."
Malawian Government Supplies 250,000 HIV-Positive Citizens With Free Antiretrovirals
President Obama on Saturday released a statement marking National HIV Testing Day that urged U.S. residents to get tested for HIV and work toward reducing the spread of the virus, Bloomberg/Arizona Daily Star reports (Bloomberg/Arizona Daily Star, 6/28). Obama said in the statement, "Each of us must take responsibility for reducing our risk of acquiring or transmitting HIV and for supporting affected individuals and communities. This means getting tested for HIV and working to end the stigma and discrimination people living with HIV face." The White House also released a video message with Obama"s statement (White House release, 6/27).
Accredited Practising Dietitian and PhD student Janice Sangster has been awarded the Dietitians
Aside from the obvious and immediate health problems that patients undergoing mechanical ventilation face, those who recover often do so with profound loss of strength and mobility that can impair their daily functioning and even lead to increased risk of morbidity and mortality down the line. Now research shows that functional status may be restored earlier to ICU patients by performing daily interruptions in sedation paired with mobilization and exercise, as led by physical and occupational therapists.
The UK spends around ÷£2.5 billion each year on dental materials to replace or strengthen teeth*. The Chewing Robot is a new biologically inspired way to test dental materials and it will be shown to the public for the first time at this year"s Royal Society Summer Science Exhibition [30 June to 4 July].
The first three guides - Clinical Engagement, Governance and Prioritising Investment - will be launched at the Practice Based Commissioning National Forum, on 1 July. A fourth guide, on Patient and Public Engagement, will be published over the summer and a fifth, on Procurement, is already in the pipeline and expected to be published in September.
A substantial number of European patients travel to other countries for fertility treatment, both because they think that they will receive better quality care abroad and in order to undergo procedures that are banned in their home country says a study of the subject launched at the 25th annual conference of the European Society of Human Reproduction and Embryology. Study co-ordinator Dr. FranÃýoise Shenfield, from University College Hospital, London, UK, said that this was the first hard evidence of considerable fertility patient migration within Europe. "Until now we have only had anecdotal evidence of this phenomenon", she said. "We think that our results will be of considerable value to patients, doctors, and policymakers."
"Epidemiology is always important and topical, though sometimes unsung," says Professor Johan Giesecke, Chief Scientist at ECDC, the European Centre for Disease Prevention and Control, "but the third applied Infectious Disease Epidemiology Conference in Stockholm in October this year will be an opportunity to put Epidemiology and infectious disease prevention and control into the spotlight; delegates will have the opportunity to discuss and share information on current and emerging infectious diseases, including influenza A (H1N1)v. The call for abstracts closes on July 3rd so there is no time to lose."
Department of Health and Human Services (HHS) Secretary Kathleen Sebelius announced that the administration will rescind all or part of three Medicaid regulations that were previously issued and delay the enforcement of a fourth regulation. Each of these rules, in whole or in part, had been subject to Congressional moratoria set to expire on July 1, 2009.
New data presented at the British Society for Allergy and Clinical Immunology (BSACI) annual meeting demonstrate that Grazax® is the first tablet treatment to provide sustained disease control in patients with grass pollen rhinoconjunctivitis (hay fever) after the treatment period ended. This is the first time disease modification by sublingual allergy immunotherapy tablets has been achieved; effectively re-setting the immune system to reduce future allergic reactions to grass pollen.
Scientists have discovered gene expression differences that could lead to better ways to classify, predict outcome, and treat juvenile idiopathic arthritis (JIA). Eventually such findings could enable doctors to target more aggressive treatment to children at risk of more severe arthritis, while those likely to have milder disease could be spared the stronger treatments that carry a greater risk of side effects. The researchers were supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health.
The Office of Tobacco Control (OTC) today (July 1, 2009) welcomed the commencement by the Department of Health and Children of further provisions of the Public Health (Tobacco) Acts, 2002 and 2004. The key provisions now commenced are:
Commenting on the publication of the results of a national patient access survey today (Tuesday, 30 June 2009) local general practitioners expressed anger that a survey which shows how well general practice is delivering care to patients has resulted in the expected loss of up to ÷£2 million of funding for local GP services. For example, one practice in Northern Ireland with a list size of over 9,000 has lost all of its funding for patient access. Despite providing both 48 hour access and offering the option for patients to book ahead, the perception of just 3% of its patients has resulted in a loss of approximately ÷£15,000 in funding for services.
Children and young adults love the thrill of skateboarding. They learn to master their skills of "riding the rail" and "catching air." But according to the American College of Foot and Ankle Surgeons (ACFAS), such tricks, while fun, can be physically demanding and cause serious foot and ankle injuries.
Even at very high doses, gadolinium-based contrast agents alone are not sufficient to cause nephrogenic systemic fibrosis (NSF) in patients with kidney problems, according to a study performed at the Mayo Clinic Florida, Jacksonville, FL. NSF is a rare and serious syndrome that leads to fibrosis of the skin, joints and even internal organs. Some research indicates NSF is caused by gadolinium-based contrast agents that are commonly used today during MR procedures.
Plans to scrap some centrally driven targets and proposals for giving doctors and nurses control of their budgets were announced by Health Minister Lord Darzi today.
Applied Genetic Technologies Corporation (AGTC), a privately-held, clinical stage biotechnology company developing novel systems to deliver human therapeutics, announces that AGTC has entered into an agreement with the National Neurovision Research Institute (NNRI), the clinical trial support organization for the Foundation Fighting Blindness(FFB), to collaborate in experiments using the AAV delivery system in the treatment of two genetic retinal diseases known to cause blindness at an early age. The research will be coordinated by AGTC and will be conducted at The University of Florida, Oregon Health & Science University, The University of Pennsylvania, and The University of British Columbia.
"Crunching data from published studies, the authors found that treating a lung-cancer patient with Erbitux, a drug that costs $80,000 for an 18-week regimen, prolongs survival by only 1.2 months," the Wall Street Journal reports. The study, which estimates that the life of each American who dies or cancer could be extended by one year at the cost of $440 billion, was published in the Journal of the National Cancer Institute.
Boston Globe columnist Derrick Jackson examines why some Ugandans do not support indoor spraying of DDT to prevent malaria. Grace Kagoro, a biology professor and environmental researcher at Mbarara University of Science and Technology, is "nervous about adding what she said could be one more shock to the soil and water," according to Jackson.
Oxfam Calls On G8 Leaders To Increase Agriculture Investment In Developing Countries
Researchers at North Carolina State University and the Georgia Institute of Technology have received a $1.2 million grant from the National Science Foundation to study whether and how video games can boost memory and thinking skills in the elderly - and then to use their findings to develop a prototype video game to do just that.
The Australian Nursing Federation (ANF) warmly congratulated Rosemary Bryant - Australia"s Chief Nursing and Midwifery officer - on her appointment as President of the International Council of Nurses (ICN).
Daily sex (or ejaculating daily) for seven days improves men"s sperm quality by reducing the amount of DNA damage, according to an Australian study presented to the 25th annual meeting of the European Society of Human Reproduction and Embryology in Amsterdam.
Whether on the trail, at the gym, or even on the front-porch steps, what happens inside your ankle in the milliseconds following a single misstep could sentence you to a lifetime of ankle trouble.
Each year in this country, one of every three people over age 65 suffers a fall, resulting in nearly 16,000 deaths. The federal government estimates that 1.8 million older adults who fall are treated each year in hospital emergency rooms for nonfatal injuries - including bruises, fractures and head trauma - and that 433,000 of those individuals need to be hospitalized because of their injuries. Research published this month in the Journal of the American Geriatrics Society has found that a significant number of those falls - an average of 129 per day - involve the use of walkers and canes, the very devices on which millions rely to help them avoid the dangers posed by falling.
Tuberculosis (TB) is a difficult infection to treat and requires six months of multiple antibiotics to cure it. To combat the TB pandemic, a shorter and simpler drug treatment would be a huge advance since most TB occurs in re-limited settings with poor public health infrastructures.
Researchers have found that men and women who feel sensitive to rejection based on their physical appearance are more likely to express interest in having cosmetic surgery than those who are less sensitive to appearance-based rejection. This effect is particularly true when people recall negative comments about their physical appearance.
Medical scientists from Southampton have contributed to a major new report published today, setting out plans to enhance the nation"s health by improving diet, increasing physical activity and cutting harmful drinking.
A just published Review in the publication "Expert Opinion on Investigational Drugs", Volume 18, Issue 7 2009, confirms the previous published information on PROSTVAC(TM). This is the most comprehensive and updated Review on PROSTVAC(TM) so far.
Tomorrow"s Council of Australian Governments (COAG) meeting is a crucial opportunity to focus on achieving concrete long-term health improvements for Indigenous people, the AMA said.
Throwing "swine flu parties" in an attempt to get immunity against the virus while it is a fairly mild form is not a good idea, the BMA said yesterday, 1 July 2009.
Previously, only a few genes had been associated with the formation of metastases in colorectal cancer. Now, researchers of the Max Delbr̿ck Center for Molecular Medicine (MDC) Berlin-Buch and Charit̩ - University Medicine Berlin, Germany, have identified 115 genes that are disregulated both in the primary tumor and in its metastases. In the future, their findings may help identify patients with aggressive tumors at an earlier stage (Gastroenterology 2009, doi:10.1053/j.gastro.2009.03.041).*
The only transdermal patch in the UK for the symptomatic treatment of moderate to severe idiopathic Restless Legs Syndrome (RLS) in adults was launched by UCB. Applied once-a-day, Neupro® (rotigotine transdermal patch) allows for continuous drug delivery to provide stable drug levels in the bloodstream 24 hours a day and improves symptom control day and night.
The results of the first Welsh GP patient survey have been published recently.
10 Years Younger, the cult Channel 4 programme with viewing figures in excess of 10 million viewers, will launch it"s first live event at Earls Court from 3rd - 5th July 09, bringing the cream of "feel good" fashion, beauty and well-being brands to the UK"s real women.
The London Borough of Croydon"s Drug & Alcohol Action Team (DAAT) is using SAS software to achieve better results in its efforts to get more people into drug treatment, reduce drug-related crime and empower the local community to resist drug misuse. SAS, the leader in business analytics software and services, gives the DAAT greater insights to commission services more effectively and target the borough"s res to where they can have the biggest impact. SAS delivers a more "joined-up" approach to allocating treatment across various agencies, which results in the most effective treatment being more quickly assigned to users who really need it.
The rate of methicillin-resistant Staphylococcus aureus (MRSA) infections in U.S. neonatal intensive care units (NICUs) has more than tripled in recent years, reports a study in the July issue of The Pediatric Infectious Disease Journal. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health, a leading provider of information and business intelligence for students, professionals, and institutions in medicine, nursing, allied health, pharmacy and the pharmaceutical industry.
A multi-national group of investigators, including a scientist at the University of North Carolina at Chapel Hill, has discovered that nearly a third of the genetic basis of schizophrenia may be attributed to the cumulative actions of thousands of common genetic variants. The effects of each of these genetic changes, innocuous on its own, add up to a significant risk for developing both schizophrenia and bipolar disorder.
A new study examining the evolution of maternal mortality rates in Spain since 1996 shows a 17% increase in deaths. This trend is linked to the widespread increase in maternal age. The highest death rates are among foreign women and those who live in the province of Malaga.
Today, during a Westminster Hall debate on the Archer Inquiry into the infection of nearly 5,000 haemophiliacs with HIV and Hepatitis C through NHS blood products, Jenny Willott, Liberal Democrat MP for Cardiff Central, revealed evidence to show that the department"s reasons for offering fair compensation to those infected is inaccurate and unjustified.
Saying that the savings from chronic disease prevention and treatment "can fill the funding gap for health care reform," the New Jersey Partnership to Fight Chronic Disease (PFCD) was joined by key state business leaders in urging federal lawmakers to "take the savings and run" with a health care reform bill that works for all Americans.
HIV-Positive Babies More Likely To Contract Deadly TB If Given BCG
A study published this week in the open access journal PLoS Medicine finds no evidence to suggest that a controversial antidote recommended by the
In this months editorial the Editors argue that-despite recent international objections- access to clean water should be recognised as a human
The U.S. should conduct research to compare the effectiveness of innovative programs aimed at preventing unintended pregnancy, according to a report issued Tuesday by a congressionally convened Institute of Medicine panel, the New York Times reports (Meier, New York Times, 7/1). The recommendations state that these strategies should include "over-the-counter access to oral contraceptives or other hormonal methods, expanding access to long-acting methods for young women, [and] providing free contraceptive methods at public clinics, pharmacies or other locations" (List of Priorities, IOM, 6/26). The report lists 100 health topics that should be prioritized as the Obama administration seeks to increase cost-effectiveness in medicine. The federal stimulus package passed earlier this year allotted $1.1 billion for comparative effectiveness research into different ways of treating certain conditions and addressing various health care issues. According to the Times, the report is a first step in an expansive effort by the administration and health experts to direct medical practice toward scientifically proven treatments, rather than a provider"s personal opinion or a medical product company"s promotional claims. Harold Sox, co-chair of the IOM panel that wrote the report and the editor of the Annals of Internal Medicine, said that based on public comments, the panel decided it was important to include pregnancy prevention and other public health issues in its recommendations (Meier, New York Times, 7/1). The report also recommends that researchers compare different comprehensive care coordination programs, such as the medical home model and chronic disease management, especially in communities known to have health disparities (Simmons, HealthLeaders Media, 6/30).
Community pharmacies are urged to register to participate in Phase 2 of the Dose Administration Aids
Commenting on the new research on Alzheimer"s by the the Institute of Psychiatry at King"s College London, Michelle Mitchell, Charity Director for Age Concern and Help the Aged said:
Johnson & Johnson has announced that Axel Ullrich, Ph.D., director of the Department of Molecular Biology at the Max Planck Institute of Biochemistry in Germany, whose discoveries have led to novel cancer therapies including Herceptin® (trastuzumab) , is the winner of the 2009 Dr. Paul Janssen Award for Biomedical Research. An independent committee of world-renowned scientists selected Dr. Ullrich, who on September 8 will receive a $100,000 prize during a ceremony in Beerse, Belgium.
Tooth-colored fillings may be more attractive than silver ones, but the bonds between the white filling and the tooth quickly age and degrade. A Medical College of Georgia researcher hopes a new nanotechnology technique will extend the fillings" longevity.
Some patients who suffer from recurrent cancer at the chest wall now have another option. The Radiation Oncology Department at Saint Barnabas Medical Center is one of a few hospitals nationwide to participate in a study which combines the use of the heat-sensitive chemotherapeutic agent ThermoDox® with microwave hyperthermia, or heat.
University of Minnesota Medical School researcher Michael Mauer, M.D., has found a treatment that significantly slows the progression of eye injury in people with type 1 diabetes, a common complication caused by this disease. By administering an antihypertensive, medication commonly prescribed to treat high blood pressure, Mauer and colleagues were able to slow progression of diabetic eye damage in more than 65 percent of participants involved in the study.
A UK survey of 575 rheumatoid arthritis sufferers highlights the importance of maintaining independence and the significant impact that early diagnosis and treatment can have. Over 94% of those surveyed claimed that their independence was compromised in some way, with over 60% saying it was compromised significantly. With earlier treatment of their disease, nearly half of the respondents felt that they would have been more independent today, making it vital that people are aware of the significance of early intervention.
New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer. The study is published in the July edition of the journal Molecular Endocrinology. This new study by Edward Filardo, MD, and his research team further supports earlier published work by the group that linked the transmembrane receptor, GPR30/GPER-1, to specific estrogen binding, rapid estrogen signaling and breast cancer metastasis. "What is exciting about this new work," says Filardo, "is that it provides some insight into the influence of GPR30 at the cellular level. It shows that estrogen action through GPR30 allows for breast tumor cell survival, and not breast tumor cell proliferation." Prior studies by Filardo"s group showed that estrogen acts through GPR30 to promote the rapid release of preformed growth factors that are tethered to the surface of breast cancer cells. Their latest study was conducted in an effort to better understand the mechanism by which GPR30 triggered the release of epidermal growth factor (EGF) polypeptides from the surface of breast cancer cells.
The single-nucleotide polymorphism (SNP) known as 2q35-rs13387042 is associated with increased risk of estrogen receptor (ER) -positive and -negative breast cancer, according to a study published online July 1 in the Journal of the National Cancer Institute.
Tekmira Pharmaceuticals Corporation (TSX:TKM) announced that it has initiated a Phase 1 human clinical trial for ApoB SNALP. ApoB SNALP, Tekmira"s lead RNAi therapeutic product candidate, is being developed as a treatment for patients with elevated low-density lipoprotein (LDL) cholesterol, or "bad" cholesterol, who are not well served by current therapy. ApoB SNALP is designed to reduce the production of apolipoprotein B (ApoB), a protein produced in the liver that plays a central role in cholesterol metabolism.
University of Cincinnati (UC) cancer and cell biologists have identified a new molecular pathway key to the development of invasive prostate cancers.
In response to the advisory committee"s recommendations to the U.S. Food and Drug Administration (FDA) to put new restrictions on acetaminophen this week, physician leaders from the American Academy of Pain Medicine (AAPM), have released the following statement:
A new study by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) reveals the genetic underpinnings of what causes lung cancer to quickly metastasize, or spread, to the brain and the bone the two most prominent sites of lung cancer relapse. The study will be published online in the journal Cell on July 2.
Scientists are to study a group of proteins that are highly effective at killing bacteria and which could hold the key to developing new types of antibiotics.
Panel physicians are increasingly offering individual health services (IHS) to patients with statutory health insurance. This is documented by Susanne Richter et al. of the Department of Social Medicine, Lubeck University, in the new edition of Deutsches Arzteblatt (Dtsch Arztebl Int 2009; 106(26): 433-9). IHS include medical health services which are not reimbursed by the health insurance funds and which the patient has to pay for himself.
Mental stress causes carotid artery dilation and increases brain blood flow. A series of ultrasound experiments, described in BioMed Central"s open access journal Cardiovascular Ultrasound, also found that this dilatory reflex was absent in people with high blood pressure.
The second of two reviews in this week´s The Lancet discusses the primary origins of the health gap. In an effort to understand these inequalities, the authors attempt to give an Indigenous perspective. It is the work of Professor Malcolm King, of the University of Alberta, Edmonton, Canada, and Scientific Director, Institute of Aboriginal Peoples" Health (Canadian Institutes of Health Research); Dr Alexandra Smith, of the University of Toronto, Canada; and Professor Michael Gracey, Unity of First People of Australia, Perth, Australia. In this review, the authors focus on North American Indigenous groups, although others are discussed.
Tinnitus (from the Latin tinnitus or "ringing") is a condition characterized by ringing, swishing, or other noises that appear to be originating in the ear or head. Not normally a dangerous or serious problem, tinnitus is usually a symptom of some other underlying condition and most often considered a nuisance. Age-related hearing loss, ear injury, foreign objects in the ear, and circulatory system problems, for example, may cause the condition.
Curcumin, the major polyphenol found in turmeric, appears to reduce weight gain in mice and suppress the growth of fat tissue in mice and cell models. Researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University (USDA HNRCA) studied mice fed high fat diets supplemented with curcumin and cell cultures incubated with curcumin.
This week Nursing Standard published some misleading and speculative information regarding the NMC"s registration fee. The story, titled "Registration fees could increase as regulator goes into black", also included factually inaccurate information about the NMC"s diversity data collection exercise which will soon be launched.
A lack of emotional intelligence leads to poor coping strategies and seriously increases the likelihood of self-harm in teenagers, claims a study published yesterday, in the British Journal of Clinical Psychology.
While CNN reports that the American Medical Association"s new president, J. James Rohack, is open to a government-funded health insurance option, others report that the system the AMA now endorses is not a public plan, but the heavily managed private plan that federal employees participate in.