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Keep Summer Swimming And Stamina Events Safe
Whether having fun, staying in shape or pushing your physical capacity to the extreme, the summer is a great time to enjoy your physical health and move more. Swimming and training for or participating in a marathon or triathalon can be rewarding activities -- and can stay fun with the proper preparation and form. The American Academy of Orthopaedic Surgeons (AAOS) offers summer athletes the following safety tips.
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Important Therapeutic Target For Breast Cancer: Newly Appreciated Membrane Estrogen Receptor
New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer. The study is published in the July edition of the journal Molecular Endocrinology. This new study by Edward Filardo, MD, and his research team further supports earlier published work by the group that linked the transmembrane receptor, GPR30/GPER-1, to specific estrogen binding, rapid estrogen signaling and breast cancer metastasis. "What is exciting about this new work," says Filardo, "is that it provides some insight into the influence of GPR30 at the cellular level. It shows that estrogen action through GPR30 allows for breast tumor cell survival, and not breast tumor cell proliferation." Prior studies by Filardo"s group showed that estrogen acts through GPR30 to promote the rapid release of preformed growth factors that are tethered to the surface of breast cancer cells. Their latest study was conducted in an effort to better understand the mechanism by which GPR30 triggered the release of epidermal growth factor (EGF) polypeptides from the surface of breast cancer cells.
News of the day
The Society For Biomolecular Sciences Delivers Annual Meeting Posters And Abstracts Online With Commenting Functionality
The Society for Biomolecular Sciences (SBS) announces the delivery of their Annual Meeting posters and abstracts with online commenting through Poster Hall 2.0 developed by Conference Archives, Inc. The SBS e-poster website, accessible to SBS members, brings together posters and abstracts from the 2008 and 2009 SBS Annual Conference & Exhibitions.
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WorldCare Clinical Implements MCC's Imaging Performance Metrics In Support Of Standardized Peformance For Imaging Trials

45th DIA Annual Meeting -- Booth # 1501 -- WorldCare Clinical, LLC (WCC), a leading imaging CRO for clinical trials in the pharmaceutical, biotechnology and medical device industries, announced that it is offering version 1.0 of the Metrics Champion Consortium (MCC) Imaging Performance Metrics to all sponsors" imaging trials beginning July 1, 2009, through its WorldPro™ technology solution. "We are pleased to announce that WCC is implementing the MCC Imaging Performance Metrics," said Dr. Asli Memisoglu, director of biostatistics and data management at WCC. "Through our innovative WorldPro technology platform, WCC is committed to support industry-wide acceptance of MCC"s performance metrics to help ensure best outcomes for our sponsors." The MCC Imaging Performance Metrics Work Group is a non-profit organization made up of biotechnology, pharmaceutical and service provider organizations that work collaboratively to develop and implement standardized performance metrics aimed at improving the efficiency and effectiveness of managing and tracking res needed to successfully run clinical trials. Additionally, WCC will offer statistical analysis of reader reliability, with metrics such as kappa and correlation coefficients, to evaluate reader performance and reliability. "It is critical for a study"s success to have a high level of agreement across readers and good consistency within assessments made by the same reader," said Dr. Richard Walovitch, chief medical officer at WCC. "WCC provides the results from these ongoing evaluations to the client and the reading team in the form of a study newsletter, which helps to facilitate communication of case studies, reader performance, and operational metrics." WCC representatives will be available at Booth # 1501 during this week"s DIA Annual Meeting in San Diego, California, to discuss its application of the MCC and other metrics in imaging trials. For more information or to schedule an appointment, contact Vanessa Conde at (978) 406-5518 or vconde@wcclinical.com. WorldCare Clinical


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