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Internists Note 'Close Alignment' With Policies In America's Affordable Health Choices Act Of 2009 -ACP Urges Approval By House Committees
The president of the American College of Physicians (ACP) today told the chairmen of the House Ways and Means, Energy and Commerce, and Education and Labor Committees that America"s Affordable Health Choices Act of 2009, H.R. 3200, is "closely aligned" with ACP policies on coverage, workforce, and payment and delivery system reform.
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Protesters Disrupt Democrats' Best-Laid Plans For Health Reform 'Conversations'
Over the weekend, a series of protests at Democratic events meant to promote health reform "organized by loose-knit coalition of conservative voters and advocacy groups, were a raucous start to what is expected to be weeks of political and ideological clashes over the health care overhaul," the New York Times reports. "Republicans said that the protests were just the beginning of spontaneous opposition to the health care proposals and that they would only gain momentum as Americans learn more about the legislation." But Democrats said they were only an effort to block discourse, and were anything but a grass-roots campaign. "This is a very coordinated effort," said one Democratic Congressman who was confronted by protestors at a grocery store (Herszenhorn and Stolberg, 8/3).
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Why Is It Important To Get A Second Opinion For A Total Knee Replacement?
While total knee surgery is a common procedure with a high success rate in the US, getting a second opinion is still recommended. Each surgeon has had a specific training and education, and more experience with certain procedures over others. Some surgeons embrace new technologies and methods while others are more traditional in their practice. Furthermore, you want to feel comfortable with your surgeon. Taking the additional steps to research, interview, and visit more than one doctor can pay off in the long run.
Endocrinology

Scientists Locate Disease Switches

New perspectives in the treatment of disease The team, led by Professor Matthias Mann of Novo Nordisk Center for Protein Research at the University of Copenhagen and the Max Planck Institute for Biochemistry in Germany, have detected 3,600 acetylation switches in 1,750 different proteins. These switches, which regulate protein functions, may prove to be a crucial factor in human ageing and the onset and treatment of diseases such as cancer, Alzheimer"s disease and Parkinson"s disease. The results of the team"s work have been published in the current edition of the journal Science. "This is more than just a technological achievement, it has also expanded the number of known acetylation switches by a factor of six, and it gives us for the first time a comprehensive insight into this type of protein modification," says Professor Mann. A given protein can perform more than one task, and how it behaves is regulated by adding a small molecule that acts as a "switch" which can turn on the different tasks. Acetylation is essential for cells" ability to function normally. Defective protein regulation plays a role in ageing and the development of diseases such as cancer, Parkinson"s and Alzheimer"s. "With the new mapping, we can now begin to study and describe how acetylation switches respond to medications that could repair the defects on them. It can have a major impact on medical care," says Professor Mann, adding that medications to repair the damaged protein regulation are already showing promising in the treatment of cancer. Cooperating proteins The team also discovered that acetylation modification occurs primarily on proteins that work together, and that these switches have much greater consequences for the organism"s function than previously thought. In one example, the function of Cdc28, an important growth protein in yeast, can be disrupted by the addition of an acetylation button, ultimately affecting the organism"s ability to survive. The results of the team"s research were published in the 17 July 2009 edition of Science. University of Copenhagen


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