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SYMBICORT(R) Added To Tiotropium Provided Clinically Significant Benefits For Patients With Severe COPD

Data presented at this year"s American Thoracic Society (ATS) congress, demonstrated that SYMBICORT® (budesonide/formoterol-TURBUHALER®, a dry powder inhaler) added to SpirivaTM (tiotropium) provided greater clinical improvements than tiotropium alone over a 12-week treatment period.1,2 Results of the CLIMB study showed that the occurrence of severe exacerbations was reduced by as much as 62 percent in patients where budesonide/formoterol was added to tiotropium (pReferences 1. Welte T, Miravitlles M, Peterson S et al. Budesonide/formoterol added to tiotropium improves the management of COPD patients. Abstract presented at American Thoracic Society (ATS) International Conference, San Diego, USA. May 15-20 2009 2. Welte T, Hartman L, Polanowski T et al. Budesonide/formoterol added to tiotropium is well tolerated and reduces risk of severe exacerbations in COPD patients. Abstract presented at American Thoracic Society (ATS) International Conference, San Diego, USA. May 15-20 2009 3. Partridge M, Karlsson N and Small I. Patient insights into the impact of COPD on morning symptoms, activities and daily life. Abstract presented at BTS 2008 4. Worth H, Peterson S, Nihlçİn U et al. Improved exercise tolerance with budesonide/formoterol vs placebo and formoterol in COPD patients. Abstract presented at American Thoracic Society (ATS) International Conference, San Diego, USA. May 15-20 2009 SYMBICORT, SYMBICORT SMART AND TURBUHALER are trademarks of the AstraZeneca group of companies -SYMBICORT is a combination of two proven medications - the inhaled corticosteroid (ICS), budesonide (Pulmicort®), and the fast-acting and long-acting bronchodilator (LABA), formoterol (Oxis®) in one inhaler - SYMBICORT is a rapid-acting combination therapy indicated for the long-term maintenance treatment of asthma, SYMBICORT SMART (Maintenance And Reliever Therapy), as well as Chronic Obstructive Pulmonary Disease (COPD), are all delivered via the SYMBICORT Turbuhaler device. SYMBICORT SMART and SYMBICORT Turbuhaler are not available in the U.S. AstraZeneca


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