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When Is It Time For Cataract Surgery?
Almost everyone who lives a long life will develop cataracts at some point. As more Americans live into their 70s and beyond, we all need to know a few cataract basics: risks and symptoms, tips that may delay onset, and how to decide when it is time for surgery, so good vision can be restored.
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Barrett's Esophagus Can Be Reversed And Cancer Risk Reduced By Radiofrequency Ablation NEJM Study Finds
Patients who have gastroesophageal reflux disease (GERD) for a prolonged period have an increased risk of developing Barrett"s esophagus, a pre-cancerous condition where the tissue lining the esophagus becomes damaged by stomach acid and transformed into something like the inside of the stomach. New research finds that radiofrequency ablation -- an endoscopic procedure involving targeted thermal energy -- was very successful at restoring the esophagus and reducing risk for cancer.
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Transplant Drug Stimulates Immune Memory
Rapamycin, a drug given to transplant recipients to suppress their immune systems, has a paradoxical effect on cells responsible for immune memory, scientists at the Emory Vaccine Center have discovered.
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IgM In Urine Acts As Prognostic Indicator In Diabetes

A marker of the likely course of diabetic nephropathy (DN) has been found. An 18-year study, published in the open access journal BMC Medicine, has shown that Immunoglobulin M (IgM) is a reliable predictor of cardiovascular complications in DN patients. Omran Bakoush, MD, PhD, led a team of researchers from Lund University, Sweden, who carried out the research. He said, "To our knowledge, this study is the first to investigate the impact of increased urine IgM excretion on DN disease progression in type 1 diabetic patients. We found that those with increased urinary IgM excretion had a higher mortality from cardiovascular causes, and higher disease progression rate to end-stage renal disease. This association is largely independent of the level of albuminuria". The researchers followed 139 patients with type 1 diabetes mellitus between 1984 and 2007. Patients with increased urine IgM excretion, measured by ELISA at the beginning of the study, were approximately three times more likely to die or progress to end-stage renal disease. Commenting on these findings, Dr Bakoush said, "These findings may offer a new approach to manage this rapidly increasing patient population. While measurement of albuminuria is routinely used to evaluate and manage patients with diabetes, increased urine IgM excretion would identify more specifically patients at risk for serious cardiovascular complications (death, and renal failure). If increased urine IgM excretion does reflects advanced atherosclerotic vascular disease, clinical trials would be justified to test whether modifying atherosclerotic factors, also decrease mortality and incidence of renal failure in diabetic patients with or without IgM-uria". Notes: Increased urine IgM excretion predicts cardiovascular events in patients with type 1 diabetes nephropathy Rafid Tofik, Ole Torffvit, Bengt Rippe and Omran Bakoush BMC Medicine (in press) Article. All articles are available free of charge, according to BioMed Central"s open access policy. Graeme Baldwin BioMed Central


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