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Media Looks At Surgeon General Nominee's Potential Influence On HIV/AIDS, Other Health Issues
The AP/Lexington Herald-Leader on Tuesday examined the nomination of Alabama physician Regina Benjamin for U.S. Surgeon General by President Obama, the history of the position and how former Surgeon Generals have addressed health issues such as HIV/AIDS (Stobbe, 7/14). According to Advocate.com, "During her speech accepting the nomination, Benjamin acknowledged her familiarity with HIV complications and issues, as her brother died at the age of 44 of an HIV-related illness. Having such a personal experience, especially a loss, due to HIV/AIDS could have a strong impact on her policy and public health campaigns, [Phil Curtis, director of government affairs at AIDS Project Los Angeles], told Advocate.com on Tuesday." The article states, "Curtis said that Benjamin has the ability to reach out to communities that have been largely underserved by efforts to reduce the rate of infection," and she "will also be able to contribute to Congress"s current debate on health care policy, including strategies for early HIV prevention, and accessibility to prescription drugs" (Garcia, 7/14).
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Parasites Ready To Jump
Transposons are mobile genetic elements found in the hereditary material of humans and other organisms. They can replicate and the new copies can insert at novel sites in the genome. Because this threatens the whole organism, molecular mechanisms have evolved which can repress transposon activity. Professor Klaus Förstemann of the Gene Center of Ludwig-Maximilians-Universität (LMU) in Munich and a team of researchers working with the fruitfly Drosophila melanogaster have now uncovered a new type of cellular defence that acts against DNA sequences present in high copy numbers inside the cell, even if they have not integrated into the genome. Small molecules of RNA (a class of nucleic acid closely related to the genetic material DNA) play the central role. "Transposons are genomic parasites, so to speak", says Förstemann. "If they are allowed to proliferate, the genome can become unstable or cancers can develop. We now want to find out whether mammalian cells possess this newly discovered defence mechanism and to elucidate precisely how it works." (EMBO Journal online, 30 July 2009.)
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Induced Pluripotent Stem Cells Repair Heart
In a proof-of-concept study, Mayo Clinic investigators have demonstrated that induced pluripotent stem (iPS) cells can be used to treat heart disease. iPS cells are stem cells converted from adult cells. In this study, the researchers reprogrammed ordinary fibroblasts, cells that contribute to scars such as those resulting from a heart attack, converting them into stem cells that fix heart damage caused by infarction. The findings appear in the current online issue of the journal Circulation.
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Heatwave Plan Updated With Advice For Those With Respiratory Problems, UK

New advice to help people with respiratory problems cope in a heatwave is published by the Department of Health. The Heatwave Plan has been updated to advise those suffering breathing problems that although ozone levels increase in hot weather, they drop in the evening. People with respiratory problems should stay inside during the hottest part of the day and windows should be kept shaded and closed when the temperature is hotter outside than inside. The benefits of insulating against both heat and cold are outlined, with information on grants that are available from government. Providing cavity insulation in houses helps keep the heat out during summer, as well as keeping homes warm and reducing fuel costs and carbon emissions during colder weather. More information on the Health Housing and Safety Rating System is also provided in the Plan. This encourages primary care trusts and local authorities to work more closely to target, assess and reduce the risk of vulnerable people living in the community who are living in homes that are too hot for their health. Yvonne Doyle, Regional Director of Public Health (South East Coast) said: "The heatwave plan urges carers to identify those most at risk before the hot weather begins. Once level 2, "Alert and Readiness" has been triggered, those running care homes are urged to take extra care. They should monitor indoor temperatures four times a day, prepare cool areas, ensure there are enough staff to keep residents cool, identify those at greatest risk and make sure everyone has access to cold water and ice." Wayne Elliott, head of health forecasting at the Met Office said: "The Department of Health"s Heatwave Plan is a vital part of the country"s preparation for coping with extreme temperatures. The prolonged spells of hot weather that can happen each summer, particularly in our towns and cities, are a very real concern for vulnerable groups." The alert levels are now described from Level 1-4, but are also given colours that mirror the traffic light system. Notes 1. See the Heatwave Plan. 2. The Heatwave Plan operates from 1 June to 15 September each year, and is based on information provided by the Met Office, which trigger alert levels according to "threshold temperatures". The four levels are: Level 1 - Summer Preparedness and Long-term Planning: Green Level 2 - Alert and Readiness: Amber Level 3 - Heatwave Action: Red Level 4 - Emergency: Red Emergency Threshold temperatures Region Day Night - (degrees Centigrade) London 32 18 South East 31 16 South West 30 15 Eastern 30 15 West Mids 30 15 East Mids 30 15 North West 30 15 Yorks & Humber 29 15 North East 28 15 3. The Energy Saving Trust is able to provide practical advice and give information about grants that might be eligible. They can be contacted on 0800 512 012. 4. The Department first published its Heatwave Plan in 2004. In May 2008, the Plan was re-launched for summer 2008. The Plan provides advice and guidance and ensures those organisations involved in providing health and social care services know what actions to take in preparation for, and in the event of, a heatwave. - The Heatwave Plan, and its advice and guidance, will help save lives. As the experience of 2003 demonstrated, particularly for those over 75, precautions need to be taken to avoid serious harm from the effects of heat on health. The heat creates strain on the heart, can make respiratory symptoms worse and cause heat exhaustion and heat stroke. - Timely preventive measures can reduce excess deaths. Extreme heat kills more quickly than the cold, so it is essential to identify those at most at risk and to act quickly if a heatwave is predicted. - The experience of 2003 is a reminder that heat can be fatal. Across Europe in 2003, the number of people who died because of the heat is estimated at 27,000. In England, there were approximately 2,000 excess deaths - 85% of which were people aged 75 and over. Those living in care homes experienced the greatest increased risk of death. The Heatwave Plan addresses this threat. - Data on where (at home, in care, in hospital etc) the individuals who died in 2003 as a result of the heatwave actually suffered the effects of excess heat is not available. ONS advise that the vast majority of the 2,000 excess deaths related to the 2003 heatwave have "hospital" recorded as the place of death. A proportion of individuals would have been admitted to hospital, having suffered the effects of extreme heat elsewhere, and subsequently died. Additionally, a proportion would have already been in hospital and the heat would have made their symptoms worse. Department of Health, UK


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